In this issue of Sleep Medicine Clinics, guest editors Drs. Brendon Yee, Stephen McNamara, and Amanda Piper bring their considerable expertise to the topic of Multi-Perspective Management of Sleep Disorders. Top experts discuss the pathophysiology of chronic respiratory failure (hypercapnic); assessment (including diagnostic tests) of chronic hypercapnic respiratory failure; overlap syndrome; managing heart failure in patients with chronic respiratory failure; the impact of new drugs in improving and maintaining respiratory function; and much more. - Contains 13 relevant, practice-oriented topics including interfaces for NIV; initiation of NIV; telemonitoring NIV; the role of high flow nasal therapy in chronic respiratory failure; airway clearance in NMD; NIV and quality of life; and more. - Provides in-depth clinical reviews on multi-perspective management of sleep disorders, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.