Barchester Towers concerns the leading clergy of the cathedral city of Barchester. The much loved bishop having died, all expectations are that his son, Archdeacon Grantly, will succeed him. Owing to the passage of the power of patronage to a new Prime Minister, a newcomer, the far more Evangelical Bishop Proudie, gains the see. His wife, Mrs. Proudie, exercises an undue influence over the new bishop, making herself as well as the bishop unpopular with most of the clergy of the diocese. Her interference to veto the reappointment of the universally popular Mr. Septimus Harding (Protagonist of Trollope's earlier novel, The Warden) as warden of Hiram's Hospital is not well received, even though she gives the position to a needy clergyman, Mr Quiverful, with 14 children to support. Even less popular than Mrs. Proudie is the bishop's new chaplain, the hypocritical and sycophantic Mr. Obadiah Slope, who decides it would be expedient to marry Harding's wealthy widowed daughter, Eleanor Bold. Slope hopes to win her favour by interfering in the controversy over the wardenship.